Kendall should stay with Zach, Ryan should remain with Annie, and Greenlee should be with Josh.
Annie was right that Zach doesn't only owe Greenlee but everyone else who had bio. material stored at that clinic during the blackout as well. Regardless of his intentipns to Kendall, he took the hopes, time, investments, and lives of so many others into his own hands.
Sean was a jerk to Ava. He doesn't have the right to say she is "nothing" because of his so-called feelings for Colby. Ava wasn't "nothing" when Sean was sleeping with her. He doesn't respect himself or women. Colby would be better off without him.
Lily should go away to school. Levin could remain on the show as Ava and she and Jonathan can become happily involved.
It is soooooooooo past due for Kathy to be revealed as Kate.